Ultrastructure of platelet formation by human megakaryocytes cultured with the Mpl ligand.

@article{Cramer1997UltrastructureOP,
  title={Ultrastructure of platelet formation by human megakaryocytes cultured with the Mpl ligand.},
  author={Elisabeth M. Cramer and Francoise Norol and Jason Guichard and Janine Breton-Gorius and William Vainchenker and Jean Marc Mass{\'e} and Najet Debili},
  journal={Blood},
  year={1997},
  volume={89 7},
  pages={
          2336-46
        }
}
The site and mechanism of platelet production by bone marrow megakaryocytes (MKs) has been the subject of extensive studies, but is still a matter of controversy. However, the recent discovery of the Mpl ligand (Mpl-l), also called megakaryocyte growth and development factor (MGDF) or thrombopoietin, has resulted in considerable progress in the understanding of the maturation of the MK lineage. To better understand the mechanism of platelet production, we examined the late stage of MK… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 35 REFERENCES

transformation to discoid platelets

  • O Behnke, ES Choi, +4 authors T Kato
  • Blood
  • 1995

Bal platelet process formation

  • K Kaushansky, S Lok, RD Holly, VC Broudy, N Lin
  • Nature
  • 1994

Recombinant human letderived microparticles express high affinity receptors for factorcMpl ligand is not a direct stimulator of proplatelet formation in mature human megakaryocytes

  • GE Gilbert, PJ Sims, +6 authors SI Kuriya
  • Am J Pathol
  • 1994

step of megakaryocytes in thrombopoiesis : Bundle formation of miPlatelets generated in vitro from proplateletdisplaying human megacrotubules in megakaryocytes

  • K Hirosawa, T Nakahata, +5 authors P Hunt
  • Cell
  • 1994

Kuang formation of megakaryocytes derived from CFU-MK

  • FJ de Sauvage, PE Hass, +8 authors SC Wong
  • Br J Haematol WP,
  • 1993

T, transformation to discoid platelets

  • ES Choi, M Hokom, T Bartley, YS Li, H Ohashi, Kato
  • Platelets 4:262,
  • 1993

The effect of the platelet-derived glycosaminoglycan

  • F Wendling, E Maraskovsky, N Debili, C Florindo, M Tepe, T Arakawa
  • Nature 21:1295,
  • 1993

Breton-Gorius penic purpura

  • N Debili, F Wendling, A Katz, J Guichard
  • Blood 18:281,
  • 1992

The presence of contractile proteins in plateletgenitor

  • P Hunt, W Vainchenker, P Wolf, N Crawford
  • Blood
  • 1992

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