Ultrastructure of nonenzymatically glycated mesangial matrix in diabetic nephropathy.

Abstract

Advanced protein glycation has been proposed as a major factor in the development of diabetic nephropathy. Advanced glycation end products (AGEs) have altered the structure of extracellular matrix component and impaired self association in vitro. To elucidate the role of AGEs in the progression of diabetic nephropathy, the present study was undertaken to… (More)

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@article{Makino1995UltrastructureON, title={Ultrastructure of nonenzymatically glycated mesangial matrix in diabetic nephropathy.}, author={Hirofumi Makino and Kenichi Shikata and Koji Hironaka and Masahiko Kushiro and Yoshimitsu Yamasaki and Hiroyuki Sugimoto and Zensuke Ota and Nobuhito Araki and Seikoh Horiuchi}, journal={Kidney international}, year={1995}, volume={48 2}, pages={517-26} }