Ultrastructure of mitochondria and the endoplasmic reticulum in renal tubules of Dahl salt-sensitive rats.

@article{He2014UltrastructureOM,
  title={Ultrastructure of mitochondria and the endoplasmic reticulum in renal tubules of Dahl salt-sensitive rats.},
  author={Xiaofeng He and Yong Liu and Kristie S Usa and Zhongmin Tian and Allen W. Cowley and Mingyu Liang},
  journal={American journal of physiology. Renal physiology},
  year={2014},
  volume={306 10},
  pages={F1190-7}
}
Metabolic and functional abnormalities in the kidney precede or coincide with the initiation of overt hypertension in the Dahl salt-sensitive (SS) rat. However, renal histological injury in SS rats is mild before the development of overt hypertension. We performed electron microscopy analysis in 7-wk-old SS rats and salt-insensitive consomic SS.13(BN) rats and Sprague-Dawley (SD) rats fed a 4% NaCl diet for 7 days. Long mitochondria (>2 μm) accounted for a significantly smaller fraction of… CONTINUE READING