Ultrastructure of Hippocampal Field CA1 in Rats after Status Epilepticus Induced by Systemic Administration of Kainic Acid

@article{Kotariya2009UltrastructureOH,
  title={Ultrastructure of Hippocampal Field CA1 in Rats after Status Epilepticus Induced by Systemic Administration of Kainic Acid},
  author={N. T. Kotariya and Tamar Z. Bikashvili and M. G. Zhvaniya and Ts. G. Chkhikvishvili},
  journal={Neuroscience and Behavioral Physiology},
  year={2009},
  volume={40},
  pages={127-130}
}
The ultrastructure of hippocampal field CA1 in rats was studied 14 days after status epilepticus induced by administration of kainic acid. Structural changes were seen in 40% of cells, predominantly interneurons, which showed both reversible changes (mitochondria with an electron-dense matrix or small numbers of short cristae, moderate dilation of rough endoplasmic reticulum (RER) cisterns, and small numbers of ribosomes) and more significant abnormalities: swollen mitochondria with very small… CONTINUE READING

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Asymmetrical synapses were often seen on small dendrites and spines , with highly osmiophilic postsynaptic zones , their synaptic terminals containing numerous synaptic vesicles and large vesicles with electron - dense cores .
Asymmetrical synapses were often seen on small dendrites and spines , with highly osmiophilic postsynaptic zones , their synaptic terminals containing numerous synaptic vesicles and large vesicles with electron - dense cores .
Asymmetrical synapses were often seen on small dendrites and spines , with highly osmiophilic postsynaptic zones , their synaptic terminals containing numerous synaptic vesicles and large vesicles with electron - dense cores .
Asymmetrical synapses were often seen on small dendrites and spines , with highly osmiophilic postsynaptic zones , their synaptic terminals containing numerous synaptic vesicles and large vesicles with electron - dense cores .
Asymmetrical synapses were often seen on small dendrites and spines , with highly osmiophilic postsynaptic zones , their synaptic terminals containing numerous synaptic vesicles and large vesicles with electron - dense cores .
Asymmetrical synapses were often seen on small dendrites and spines , with highly osmiophilic postsynaptic zones , their synaptic terminals containing numerous synaptic vesicles and large vesicles with electron - dense cores .
Asymmetrical synapses were often seen on small dendrites and spines , with highly osmiophilic postsynaptic zones , their synaptic terminals containing numerous synaptic vesicles and large vesicles with electron - dense cores .
Structural changes were seen in 40% of cells , predominantly interneurons , which showed both reversible changes ( mitochondria with an electron - dense matrix or small numbers of short cristae , moderate dilation of rough endoplasmic reticulum ( RER ) cisterns , and small numbers of ribosomes ) and more significant abnormalities : swollen mitochondria with very small numbers of cristae , which were partially degraded , some with damaged mitochondrial membranes , along with pathologically damaged RER components and focal or peripheral chromatolysis .
Structural changes were seen in 40% of cells , predominantly interneurons , which showed both reversible changes ( mitochondria with an electron - dense matrix or small numbers of short cristae , moderate dilation of rough endoplasmic reticulum ( RER ) cisterns , and small numbers of ribosomes ) and more significant abnormalities : swollen mitochondria with very small numbers of cristae , which were partially degraded , some with damaged mitochondrial membranes , along with pathologically damaged RER components and focal or peripheral chromatolysis .
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