Ultrastructural study of the cornea in a bone marrow-transplanted Hurler syndrome patient.

@article{Huang1996UltrastructuralSO,
  title={Ultrastructural study of the cornea in a bone marrow-transplanted Hurler syndrome patient.},
  author={Yu-ying Huang and A. J. Bron and Keith M. Meek and Ashok Vellodi and B Mcdonald},
  journal={Experimental eye research},
  year={1996},
  volume={62 4},
  pages={377-87}
}
This case report describes a 14-year-old girl with Hurler syndrome, who had received a successful bone marrow-transplant at the age of two. Corneal clouding was present at the time of transplant and has only partially cleared. A right penetrating keratoplasty was performed and the corneal specimen was examined by light microscopy, transmission electron microscopy with Cuprolinic blue staining for proteoglycans, and low-angle X-ray diffraction. The results show the corneal stroma to be disrupted… CONTINUE READING

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