Ultrastructural study of hippocampal cortex neurons in an experimental model of valproate encephalopathy.

Abstract

Valproate (VPA) is a widely used antiepileptic drug. A serious neurological-outcome defined as valproate encephalopathy (VE) may rarely occur during VPA therapy. Structural abnormalities within neurons are postulated as one of the reasons for VE. The aim of this study was to assess the ultrastructure of neurons in the hippocampal cortex during the course of… (More)
DOI: 10.5603/FHC.2013.005

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