Ultrastructural study of effect of ACTH4–10 on nerve regeneration; Axons become larger in number and smaller in diameter

@article{Bijlsma1983UltrastructuralSO,
  title={Ultrastructural study of effect of ACTH4–10 on nerve regeneration; Axons become larger in number and smaller in diameter},
  author={W. A. Bijlsma and E. van Asselt and Henk Veldman and Frans G. I. Jennekens and Peter C. Schotman and Willem Hendrik Gispen},
  journal={Acta Neuropathologica},
  year={1983},
  volume={62},
  pages={24-30}
}
Electron-microscopic analysis of the regenerating sciatic nerve in the rat showed that ACTH4–10 treatment stimulated the number of regenerating myelinated and unmyelinated fibers to a similar degree. Fourteen days following a crush lesion of the sciatic nerve, 23% more regenerating fibers were present in the ACTH4–10-treated group of animals. The increase in number of regenerating fibers was accompanied by a comparable decrease in axon diameter. The ACTH4–10 treatment did not change the number… CONTINUE READING

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