Ultrastructural studies on the replication and morphogenesis of Nairobi sheep disease virus, aNairovirus

@article{Rwambo1996UltrastructuralSO,
  title={Ultrastructural studies on the replication and morphogenesis of Nairobi sheep disease virus, aNairovirus},
  author={Paul M Rwambo and Michael Shaw and Fred R. Rurangirwa and J. Demartini},
  journal={Archives of Virology},
  year={1996},
  volume={141},
  pages={1479-1492}
}
TheNairovirus Nairobi sheep disease virus (NSDV) affects sheep and goats causing severe hemorrhagic gastroenteritis and high mortality. Replication and morphogenesis of NSDV was determined by electron microscopic examination of ultra-thin sections of 143B and BHK-21 cells at varying times after infection. By 4h post-infection (p.i.) of 143B cells, virions budding from the luminal side of the bilayer membrane of smooth membrane vesicles were observed. Morphologically mature virus particles were… CONTINUE READING
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