Ultrastructural observations in the carbonyl iron-fed rat, an animal model for hemochromatosis.

@article{Iancu1987UltrastructuralOI,
  title={Ultrastructural observations in the carbonyl iron-fed rat, an animal model for hemochromatosis.},
  author={Theodore C. Iancu and Roberta J. Ward and Timothy J. Peters},
  journal={Virchows Archiv. B, Cell pathology including molecular pathology},
  year={1987},
  volume={53 4},
  pages={208-17}
}
Rats fed a carbonyl iron-supplemented diet for 4-15 months were studied for iron content and morphologic changes in the liver, spleen, intestinal mucosa, pancreas and heart. All organs had an increased iron content measured by atomic absorption, with the highest concentrations in the liver and spleen. The periportal distribution of stored iron in the liver… CONTINUE READING