Ultrastructural morphometry of sparsely granulated prolactin cell adenomas of the human pituitary.

@article{McComb1978UltrastructuralMO,
  title={Ultrastructural morphometry of sparsely granulated prolactin cell adenomas of the human pituitary.},
  author={Dave McComb and K{\'a}lm{\'a}n Kov{\'a}cs},
  journal={Acta endocrinologica},
  year={1978},
  volume={89 3},
  pages={521-9}
}
Fifteen sparsely granulated prolactin-producing adenomas and 10 nontumourous adenohypophyses, removed by surgical hypophysectomy, have been studied using morphometry at the electron microscopic level. Compared to non-tumourous prolactin cells, sparsely granulated adenomatous prolactin cells showed a significant decrease in diameter and volume density of secretory granules and an increased volume density of rough-surfaced endoplasmic reticulum and Golgi apparatus. The volume density of… CONTINUE READING