Ultrastructural localization of pemphigus vulgaris and pemphigus foliaceus antigens in cultured human squamous carcinoma cells.

@article{Akiyama1991UltrastructuralLO,
  title={Ultrastructural localization of pemphigus vulgaris and pemphigus foliaceus antigens in cultured human squamous carcinoma cells.},
  author={Masashi Akiyama and Takashi Hashimoto and Makoto Sugiura and Takeji Nishikawa},
  journal={The British journal of dermatology},
  year={1991},
  volume={125 3},
  pages={233-7}
}
The ultrastructural localization of the pemphigus vulgaris (PV) and pemphigus foliaceus (PF) antigens in cultured human squamous carcinoma cells was observed using immunogold electron microscopy. Both the PV and PF autoantibodies bound only to the extracellular portion of the desmosomal structures. After incubation at 37 degrees C, the PV antigen-antibody… CONTINUE READING