Ultrastructural localization of a neutral and basic amino acid transporter in rat kidney and intestine.

@article{Pickel1993UltrastructuralLO,
  title={Ultrastructural localization of a neutral and basic amino acid transporter in rat kidney and intestine.},
  author={Virginia M Pickel and M J Nirenberg and Joanne P Chan and Rachel Mosckovitz and Sidney Udenfriend and Suresh S. Tate},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1993},
  volume={90 16},
  pages={
          7779-83
        }
}
A sodium-independent neutral and basic amino acid transporter (NBAT) from rat kidney was recently cloned and its amino acid sequence deduced. We used light and electron microscopic immunoperoxidase labeling to determine the cellular localization of NBAT in rat kidney and small intestine. The localization was carried out using site-directed antisera raised against synthetic peptides within NBAT. The most prominent localization of NBAT was in microvilli of epithelial cells lining renal proximal… CONTINUE READING
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