Ultrastructural immunodetection of osteopontin and osteocalcin as major matrix components of renal calculi.

@article{McKee1995UltrastructuralIO,
  title={Ultrastructural immunodetection of osteopontin and osteocalcin as major matrix components of renal calculi.},
  author={M. D. McKee and Antonio Nanci and Saeed R. Khan},
  journal={Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research},
  year={1995},
  volume={10 12},
  pages={1913-29}
}
The organic matrix of renal calculi has long been considered to influence the crystal growth that occurs in these pathological mineral deposits. Recent advances in characterizing individual organic moieties from mineralized tissues in general and the combined use of antibodies raised against these molecules with different immunocytochemical approaches have allowed their precise distribution to be visualized in a variety of normal and pathological mineralized tissues. The present ultrastructural… CONTINUE READING

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