Ultrastructural fiber typing in normal and diseased human muscle.

  title={Ultrastructural fiber typing in normal and diseased human muscle.},
  author={Claire Margaret Payne and Lawrence Z. Stern and Richard G. Curless and L K Hannapel},
  journal={Journal of the neurological sciences},
  volume={25 1},
The differential staining of the 3 fiber types for oxidative enzyme activity at the histochemical level provides the basis of their identification at the ultrastructural level. Type I fibers have the largest and most numerous mitochondria, the Type IIA smaller and less numerous mitochondria, and Type IIB have the smallest and least numerous mitochondria as studied in 4 patients without neuromuscular disease. Type I fibers could be distinguished from Type II fibers on the basis of mean Z-line… CONTINUE READING