Ultrastructural features of the astrocytes involved in the phagocytic response to excitotoxins and anoxia in vitro.

@article{Matyja1999UltrastructuralFO,
  title={Ultrastructural features of the astrocytes involved in the phagocytic response to excitotoxins and anoxia in vitro.},
  author={Ewa Matyja},
  journal={Folia neuropathologica},
  year={1999},
  volume={37 2},
  pages={65-74}
}
  • Ewa Matyja
  • Published 1999 in Folia neuropathologica
The present ultrastructural studies demonstrate the morphological evidence of phagocytic response of astroglia to excitotoxins and anoxia in vitro. The studies were performed on organotypic cultures of the rat hippocampus exposed to various excitatory amino acids (QUIN, KA, GLU) or pure nitrogen atmosphere. In all these pathological conditions, the extensive neuronal degeneration was accompanied by marked astroglial reaction. The astrocytes revealed ultrastructural abnormalities consisting of… CONTINUE READING