Ultrastructural features of canine neuroaxonal dystrophy in a Papillon dog

Abstract

Neuroaxonal dystrophy (NAD) is a neurodegenerative disease characterized by severe axonal swelling (spheroids) throughout the nervous system. In dogs, NAD has been reported in several breeds and a missense mutation in PLA2G6 gene has recently been identified in the Papillon dog NAD. Here we performed ultrastructural analysis to clarify the detailed… (More)
DOI: 10.1292/jvms.17-0487

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