Ultrastructural effects of cadmium on the rat epididymis.

  title={Ultrastructural effects of cadmium on the rat epididymis.},
  author={Fabio L. Sacerdote and Juan Carlos Cavicchia},
  journal={International journal of andrology},
  volume={6 6},
The short-term effect of a subcutaneous injection of 3 mumol of cadmium chloride/100 g body weight were examined 90 min later in male rats. The main target of cadmium, as shown by electron microscopy, was the endothelial lining of capillaries of the caput epididymidis. Intercellular junctions between endothelial cells were disorganized, ranging from slight separation between cytoplasmic leaflets to wide gaps which communicated freely with the pericapillary tissue. Disruption of platelets and… CONTINUE READING