Ultrastructural characterization of spermatogenesis and its evolutionary conservation in the germline: germinal granules in mammals.

@article{Chuma2009UltrastructuralCO,
  title={Ultrastructural characterization of spermatogenesis and its evolutionary conservation in the germline: germinal granules in mammals.},
  author={Shinichiro Chuma and Mihoko Hosokawa and Takashi Tanaka and Norio Nakatsuji},
  journal={Molecular and cellular endocrinology},
  year={2009},
  volume={306 1-2},
  pages={17-23}
}
Germline cells of many animals possess characteristic cytoplasmic structures termed germinal granules or nuage. Germinal granules are ribonucleoprotein (RNP) amorphous aggregates lacking limiting membranes, and their molecular composition is evolutionarily conserved in divergent species. Studies on germinal granules in several model animals, such as Drosophila, C. elegans and Xenopus, have mainly focused on the asymmetric partitioning of the structures to prospective germ cells during early… CONTINUE READING

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