Ultrastructural changes in the rectal mucosa of patients with rheumatoid arthritis.

@article{Struthers1985UltrastructuralCI,
  title={Ultrastructural changes in the rectal mucosa of patients with rheumatoid arthritis.},
  author={G. R. Struthers and Catherine A. Hollywell and Christopher J. Morris and K. W. Walton and Paul A. Bacon},
  journal={Annals of the rheumatic diseases},
  year={1985},
  volume={44 9},
  pages={625-30}
}
The rectal mucosa from patients with severe rheumatoid arthritis has been examined by electron microscopy. Initially the patients were biopsied for investigation into the diagnosis of amyloidosis or vasculitis, which proved to be negative. A range of ultrastructural abnormalities was found which included proliferation of the rough endoplasmic reticulum, mitochondrial inclusions, association of the mitochondria with cytoplasmic filaments, and marked increase in the number of iron containing… CONTINUE READING