Ultrastructural analysis of neurofibrillary tangles of Alzheimer's disease using computerized digital processing

Abstract

The ultrastructure of neurofibrillary tangles of Zlzheimer's disease was analyzed by computerized digital processing of electron micrographs. Processing of the electron micrographs consists of four steps: digitizing the electron micrograph, Fourier transformation, noise filtering and inverse Fourier transformation and Laplacian operation. In the present… (More)
DOI: 10.1007/BF00687141

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