Ultrastructural analysis of 3 hyaluronic acid soft-tissue fillers using scanning electron microscopy.

@article{Flynn2015UltrastructuralAO,
  title={Ultrastructural analysis of 3 hyaluronic acid soft-tissue fillers using scanning electron microscopy.},
  author={Timothy Corcoran Flynn and David H. Thompson and Seok-hee Hyun and David James Howell},
  journal={Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]},
  year={2015},
  volume={41 Suppl 1},
  pages={
          S143-52
        }
}
BACKGROUND Although hyaluronic acid (HA) specifications such as molecular weight and particle size are fairly well characterized, little information about HA ultrastructural and morphologic characteristics has been reported in clinical literature. OBJECTIVE To examine uniformity of HA structure, the effects of extrusion, and lidocaine dilution of 3 commercially available HA soft-tissue fillers. MATERIALS AND METHODS Using scanning electron microscopy and energy-dispersive x-ray analysis… CONTINUE READING
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