Ultrastructural Imaging of Salmonella–Host Interactions Using Super‐resolution Correlative Light‐Electron Microscopy of Bioorthogonal Pathogens

@inproceedings{Elsland2018UltrastructuralIO,
  title={Ultrastructural Imaging of Salmonella–Host Interactions Using Super‐resolution Correlative Light‐Electron Microscopy of Bioorthogonal Pathogens},
  author={Daphne M. van Elsland and S{\'i}lvia Pujals and Thomas Bakkum and Erik Bos and Nikolaos Oikonomeas-Koppasis and Ilana Berlin and Jacques Neefjes and Annemarie H. Meijer and Abraham J Koster and Lorenzo Albertazzi and Sander Iza{\"a}k van Kasteren},
  booktitle={Chembiochem : a European journal of chemical biology},
  year={2018}
}
The imaging of intracellular pathogens inside host cells is complicated by the low resolution and sensitivity of fluorescence microscopy and by the lack of ultrastructural information to visualize the pathogens. Herein, we present a new method to visualize these pathogens during infection that circumvents these problems: by using a metabolic hijacking approach to bioorthogonally label the intracellular pathogen Salmonella Typhimurium and by using these bioorthogonal groups to introduce… CONTINUE READING
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Membrane Trafficking, 2nd ed

  • J. Tam, D. Merino, J. Neurochem
  • New York,
  • 2014
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