Ultrastructural Criteria of Cardiomyocyte Regeneratory and Plastic Insufficiency in Anthracycline Cardiomyopathy

Abstract

We analyzed the dynamics of ultrastructural changes in cardiomyocytes in experimental chronic anthracycline cardiomyopathy. Doxorubicin-induced changes in cardiomyocytes were characterized by a specific combination of ultrastructural changes, which can be regarded as markers of the development of regeneratory and plastic insufficiency. These markers include… (More)
DOI: 10.1007/s10517-005-0325-z

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