Ultrastructural Characterization of SARS Coronavirus

  title={Ultrastructural Characterization of SARS Coronavirus},
  author={C. S. Brown E. L. Goldsmith and Kathleen M. Tatti and Thomas Ksiazek and Pierre E. Rollin and James A. Comer and William W. Lee and Paul A Rota and Bettina Bankamp and William J. Bellini and Sherif R. Zaki},
  booktitle={Emerging infectious diseases},
Severe acute respiratory syndrome (SARS) was first described during a 2002-2003 global outbreak of severe pneumonia associated with human deaths and person-to-person disease transmission. The etiologic agent was initially identified as a coronavirus by thin-section electron microscopic examination of a virus isolate. Virions were spherical, 78 nm in mean diameter, and composed of a helical nucleocapsid within an envelope with surface projections. We show that infection with the SARS-associated… CONTINUE READING


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