Ultrastructural, immunofluorescence, and RNA evidence support the hypothesis of a "new" virus associated with Kawasaki disease.

@article{Rowley2011UltrastructuralIA,
  title={Ultrastructural, immunofluorescence, and RNA evidence support the hypothesis of a "new" virus associated with Kawasaki disease.},
  author={Anne H. Rowley and Susan C Baker and Stanford T. Shulman and Kenneth H Rand and Maria Tretiakova and Elizabeth J Perlman and Francesca Garcia and Nuzhath F Tajuddin and Linda M. Fox and Julia He Huang and J. Carter Ralphe and Kei S Takahashi and Jared Flatow and Simon Lin and Mitra B. Kalelkar and Benjamin J Soriano and Jan Marc Orenstein},
  journal={The Journal of infectious diseases},
  year={2011},
  volume={203 7},
  pages={1021-30}
}
BACKGROUND Intracytoplasmic inclusion bodies (ICI) have been identified in ciliated bronchial epithelium of Kawasaki disease (KD) patients using a synthetic antibody derived from acute KD arterial IgA plasma cells; ICI may derive from the KD etiologic agent. METHODS Acute KD bronchial epithelium was subjected to immunofluorescence for ICI and cytokeratin, high-throughput sequencing, and transmission electron microscopy (TEM). Interferon pathway gene expression profiling was performed on KD… CONTINUE READING
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