Ultrasound-triggered local anaesthesia

  title={Ultrasound-triggered local anaesthesia},
  author={Alina Y. Rwei and Juan L. Paris and Bingxing Wang and Weiping Wang and Christopher D. Axon and Mar{\'i}a Vallet-Reg{\'i} and Robert S Langer and Daniel S. Kohane},
  booktitle={Nature Biomedical Engineering},
On-demand relief of local pain would allow patients to control the timing, intensity and duration of nerve blocks in a safe and non-invasive manner. Ultrasound would be a suitable trigger for such a system, as it is in common clinical use and can penetrate deeply into the body. Here, we demonstrate that ultrasound-triggered delivery of an anaesthetic from liposomes allows the timing, intensity and duration of nerve blocks to be controlled by ultrasound parameters. On insonation, the… CONTINUE READING
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Ultrasound guidance compared with electrical neurostimulation for peripheral nerve block: a systematic NAtURe BioMeDiCAL eNgiNeeRiNg | VOL 1 | AUGUST

  • M. S. Abrahams, M. F. Aziz, R. F. Fu, J. L. Horn
  • Macmillan Publishers Limited, part of Springer…
  • 2017

a multicentre, randomized, double-blind, placebo-controlled, parallel-design trial

  • Hagen, N. A. et al. Tetrodotoxin for moderate to severe canc pain
  • Pain Res. Manag. 2017, 7212713
  • 2017

Ultrasonic neuromodulation

  • O. Naor, S. Krupa, S. Shy
  • J. Neural Eng. 13,
  • 2016

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