Ultrasound-triggered local anaesthesia

@inproceedings{Rwei2017UltrasoundtriggeredLA,
  title={Ultrasound-triggered local anaesthesia},
  author={Alina Y. Rwei and Juan L. Paris and Bingxing Wang and Weiping Wang and Christopher D. Axon and Mar{\'i}a Vallet-Reg{\'i} and Robert S Langer and Daniel S. Kohane},
  booktitle={Nature Biomedical Engineering},
  year={2017}
}
On-demand relief of local pain would allow patients to control the timing, intensity and duration of nerve blocks in a safe and non-invasive manner. Ultrasound would be a suitable trigger for such a system, as it is in common clinical use and can penetrate deeply into the body. Here, we demonstrate that ultrasound-triggered delivery of an anaesthetic from liposomes allows the timing, intensity and duration of nerve blocks to be controlled by ultrasound parameters. On insonation, the… CONTINUE READING
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