Ultrasound tissue characterization by integrated backscatter for analyzing Fluorouracil induced myocardial damage.

@article{Ceyhan2005UltrasoundTC,
  title={Ultrasound tissue characterization by integrated backscatter for analyzing Fluorouracil induced myocardial damage.},
  author={Ceyhun Ceyhan and Nezih Meydan and Sabri Barutça and Tarkan Tekten and Alper Osman Onbasili and Banu Turgurt Ozturk and Selim Unal},
  journal={Echocardiography},
  year={2005},
  volume={22 3},
  pages={233-8}
}
BACKGROUND 5-Fluorouracil (5-FU) cardiotoxicity is a well-known clinical phenomenon whose pathophysiology remains controversial. Cyclic variation of integrated backscatter (CVIBS) assesses acoustic properties of myocardium that may reflect both contractility and structural changes. The aim of this study was to evaluate CVIBS alterations in cancer patients under high-dose leucovorin and infusional 5-FU (HDLV5FU) chemotherapy. METHOD We prospectively evaluated 37 cancer patients under HDLV5FU… CONTINUE READING