Ultrasound-guided Intracardiac Injection of Human Mesenchymal Stem Cells to Increase Homing to the Intestine for Use in Murine Models of Experimental Inflammatory Bowel Diseases.

Abstract

Crohn's disease (CD) is a common chronic inflammatory disease of the small and large intestines. Murine and human mesenchymal stem cells (MSCs) have immunosuppressive potential and have been shown to suppress inflammation in mouse models of intestinal inflammation, even though the route of administration can limit their homing and effectiveness 1,3,4,5… (More)
DOI: 10.3791/55367

Cite this paper

@article{Dave2017UltrasoundguidedII, title={Ultrasound-guided Intracardiac Injection of Human Mesenchymal Stem Cells to Increase Homing to the Intestine for Use in Murine Models of Experimental Inflammatory Bowel Diseases.}, author={Maneesh Dave and Paola Menghini and Keiki Sugi and Rodrigo A. Somoza and Zhenghong Lee and Mukesh Jain and Arnold I. Caplan and Fabio Cominelli}, journal={Journal of visualized experiments : JoVE}, year={2017}, volume={127} }