Ultrasound enhancement of cationic lipid-mediated gene transfer to primary tumors following systemic administration

Abstract

The impact of a localized application of ultrasound on gene transfer to primary tumors following systemic administration of cationic lipid based transfection complexes was investigated. We have previously shown that systemic administration of DOTMA (N-[(1-(2–3-dioleyloxy) propyl)]-N-N-N-trimethylammonium chloride):cholesterol-based transfection complexes to… (More)
DOI: 10.1038/sj.gt.3301302

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