Ultrasound detection of nanoparticle contrast agents for multimodal molecular imaging

@article{Conversano2011UltrasoundDO,
  title={Ultrasound detection of nanoparticle contrast agents for multimodal molecular imaging},
  author={Francesco Conversano and Antonio Greco and Ernesto Casciaro and Sergio Casciaro and Andrea Ragusa and Massimo Mischi and Aim{\'e} Lay-Ekuakille},
  journal={2011 IEEE International Symposium on Medical Measurements and Applications},
  year={2011},
  pages={477-481}
}
Aim of the present work was, first, to demonstrate feasibility and usefulness of subharmonic imaging of silica nanospheres (SiNSs) at diagnostic ultrasound (US) frequencies and, second, to investigate the acoustic effectiveness of a new class of multimodal nanocomposite contrast agents, towards dual mode investigations combining US and magnetic resonance imaging (MRI). We employed SiNSs of variable diameter (160 nm, 330 nm and 660 nm) dispersed in different volume concentrations (range 0.07–0.8… CONTINUE READING

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