Ultrasound Localization Microscopy and Super-Resolution: A State of the Art

@article{Couture2018UltrasoundLM,
  title={Ultrasound Localization Microscopy and Super-Resolution: A State of the Art},
  author={Olivier Couture and Vincent Hingot and Baptiste Heiles and Pauline Muleki-Seya and Mickael Tanter},
  journal={IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control},
  year={2018},
  volume={65},
  pages={1304-1320}
}
  • O. CoutureV. Hingot M. Tanter
  • Published 26 June 2018
  • Medicine
  • IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
Because it drives the compromise between resolution and penetration, the diffraction limit has long represented an unreachable summit to conquer in ultrasound imaging. Within a few years after the introduction of optical localization microscopy, we proposed its acoustic alter ego that exploits the micrometric localization of microbubble contrast agents to reconstruct the finest vessels in the body in-depth. Various groups now working on the subject are optimizing the localization precision… 
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Super-resolution Ultrasound Imaging.

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Microvascular flow dictates the compromise between spatial resolution and acquisition time in Ultrasound Localization Microscopy

This work studied the reconstruction of a coronal slice of a rat’s brain during a continuous microbubble injection close to clinical concentrations and finds that the biggest vessels can be reconstructed in seconds but that it would take tens of minutes to map the entire capillary network.

A Review of Clinical Applications for Super-resolution Ultrasound Localization Microscopy

Clinicians are provided with an up-to-date review of ULM technology, and a practical guide for implementing ULM in clinical research and practice, and areas where ULM may not be a better alternative to CEUS.

Development of Simultaneous Optical Imaging and Super-Resolution Ultrasound to Improve Microbubble Localization Accuracy

Acoustic super-resolution (SR) has the potential to visualize microvasculature by localizing individual microbubble (MB) signals. Currently, all detected signals are processed and localized…

Ultrafast 3D Ultrasound Localization Microscopy Using a 32 $\times$ 32 Matrix Array

This paper demonstrates the feasibility of 3-D ultrafast ultrasound localization microscopy in vitro and opens up the way toward volumetric ULM in vivo.

Superharmonic Ultrasound for Motion-Independent Localization Microscopy: Applications to Microvascular Imaging From Low to High Flow Rates

Superharmonic imaging is applied to ULM and an average improvement in SNR of 10.3-dB in vitro when compared with the standard singular value decomposition filter approach and an increase inSNR at low flow from 5 to 16.5 dB.

Transformer for Ultrafast Ultrasound Localization Microscopy

Ultrasound localization microscopy (ULM), which allows for the detection of subwavelength acoustic scattering of intravenously injected microbubbles, enabling non-invasive visualization of…

Sparse channel sampling for ultrasound localization microscopy (SPARSE-ULM)

The results suggest that a compromise can be found between the number of channels and the quality of the reconstructed vascular network and demonstrate feasibility of performing ULM with a reduced number of channel in receive, paving the way for low-cost devices enabling high-resolution vascular mapping.

Microvascular Imaging with Super-Resolution Ultrasound

Super-resolution ultrasound imaging (SRUS) is a branch of ultrasound techniques aiming to image and quantify the vasculature beyond the diffraction limit [1]. Going beyond the diffraction limit of…
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