Ultrasonographically detectable markers of fetal chromosomal abnormalities.

@article{Nicolaides1992UltrasonographicallyDM,
  title={Ultrasonographically detectable markers of fetal chromosomal abnormalities.},
  author={Kypros H. Nicolaides and Rosalinde Johanna Maria Snijders and Christine M. Gosden and Colin Berry and Stephen La Vern Campbell},
  journal={Lancet},
  year={1992},
  volume={340 8821},
  pages={704-7}
}
Screening for fetal chromosomal abnormalities on the basis of maternal age has not resulted in a substantial fall in the proportion of infants born with an abnormal karyotype. Most fetuses with major chromosomal abnormalities have defects that can be recognised on detailed ultrasonographic examination. Therefore, provided the cardinal signs of each… CONTINUE READING