Ultrasonographic, Axial, and Peripheral Measurements in Female Patients with Benign Hypermobility Syndrome

  title={Ultrasonographic, Axial, and Peripheral Measurements in Female Patients with Benign Hypermobility Syndrome},
  author={Jo Nijs and Els Van Essche and Matthias De Munck and Jan Dequeker},
  journal={Calcified Tissue International},
Abstract. Twenty-five female Caucasians, aged 19–57 years, with the hypermobility syndrome had bone density measurements using established noninvasive techniques such as dual X-ray absorptiometry (DXA), single photon absorptiometry (SPA), heel ultrasound (US), and peripheral computed tomography (pQCT) acquisitions of the radius. As a group, comparisons of the different bone indices with the corresponding age-matched reference population resulted in normal z-scores for the arial densities… 

Hypermobility syndrome increases the risk for low bone mass

It is suggested that pre-menopausal women with joint hypermobility have lower bone mineral density when compared to the controls andhypermobility increases the risk for low bone mass.

Benign hypermobility syndrome: a case report

A 13 year-old female presented with long-standing complaints of anterior knee pain which increased at night in particular, also pain and stiffness in her pain, and laboratory parameters and con-ventional radiographic observations were normal.

The prevalence of joint hypermobility among high school students

Although hypermobility does not seem to be very problematic in young people, as in the focus group, it is important for physicians to recognize this problem to ensure correct diagnosis and treatment, since it may lead to mimic rheumatic diseases in the future.

Joint hypermobility in fibromyalgia patients has no impact on tests for disease severity

In general, the presence of benign joint hypermobilty with fi bromyalgia does not change the disease appearance, and hypermobile patients do not appear to differ in disease severity from the rest of the fi b limpalgia population.

A study exploring the prevalence of Joint Hypermobility Syndrome in patients attending a Musculoskeletal Triage Clinic

It is found that patients with JHS are likely toPresent with a greater number of painful joints and are more likely to present with wrist/hand pain as their main problem than those without JHS.

Joint laxity in the parents of children with temporary brittle bone disease

It is drawn attention to the likely autosomal dominant inheritance of this risk factor for temporary brittle bone disease as well as the potential value of assessing parental joint laxity in evaluating children with fractures.

Joint Hypermobility: Association with Musculoskeletal Injuries in Young Adult Females

A small, significant positive correlation was found between raw hypermobility score and musculoskeletal injury score based on self‐report, and additional research is needed to determine what influences injury rates in the person withhypermobility, and what interventions are most beneficial to prevent further injury.

Dietary Restriction Does Not Adversely Affect Bone Geometry and Mechanics in Rapidly Growing Male Wistar Rats

It is shown that a level of dietary restriction that is less severe than many studies, and without micronutrient compensation does not adversely affect tibial and vertebral mechanical properties in young growing male rats when normalized for body mass.

Ehlers–Danlos syndrome-related genes and serum strontium, zinc, and lithium levels in generalized joint hypermobility: a case-control study

The results showed that women with GJH possessed significantly lower Li and higher Zn and Sr levels than the controls and provide valuable basal levels for conducting gene function analysis of joint hypermobility-related connective tissue disorders.

Hypermobility, the Ehlers-Danlos syndromes and chronic pain.

Chronic pain in JHS and EDS patients often is inadequately controlled by traditional analgesics and physical therapy, and future studies addressing the nature and mediators of chronic pain are needed in order to potentially identify novel targets for therapeutic intervention and optimise treatment.



Bone mineral status of women with Marfan syndrome.

Assessment of bone mineral density in women with Marfan syndrome.

It is concluded that Marfan syndrome is not associated with a clinically significant increase in the risk of osteoporotic fracture and bone mineral density was very similar in the authors' Marfan women as compared with the two reference populations.

Bone mineral density in children with mild osteogenesis imperfecta.

Dual-energy X-ray absorptiometry (DEXA) is an objective, reproducible and sensitive method of measurement of BMD in children and may help to establish the diagnosis, to assess prognosis and possibly to monitor the response to different types of treatment.

Extra-articular features of benign joint hypermobility syndrome.

Patients with BJHS do not have an increased prevalence of significant cardiac, bone, skin or eye abnormalities, helping differentiate BJHS from other more serious hereditary disorders of connective tissue.

Assessment of the skeletal status by peripheral quantitative computed tomography of the forearm: Short‐term precision in vivo and comparison to dual X‐ray absorptiometry

  • S. GramppP. Lang H. Genant
  • Biology, Medicine
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
  • 1995
The measurement of cortical bone in the distal radius proved to be a good predictor of vertebral fracture status and was a good indicator of age‐related skeletal change and emphasize the importance of cortical measurements when using pQCT of the radius to assess osteoporosis.

Precision and Discriminatory Ability of Calcaneal Bone Assessment Technologies

  • S. GreenspanM. Bouxsein E. Orwoll
  • Medicine
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
  • 1997
Although the precision is variable, the calcaneal QUS and SEXA instruments can discriminate between osteoporotic patients and young normal controls and appear to be a useful technique for assessment of osteoporeosis.

Clinical and anthropometric correlates of bone mineral acquisition in healthy adolescent girls.

Bone mineral apparent density (BMAD) is presented, which is BMC normalized to a derived bone reference volume, which minimizes the effect of bone geometry and allows comparisons of mineral status among bones of similar shape but different size.

Influence of Bone Quality on Precision of Calcaneal Ultrasonometry

It was found that the median precision error for BUA was 1.99% for normal bone and 1.44% for abnormal bone, and Precision error appears to decrease slightly at lower values for calcaneal variables.

Osteoporosis and the Marfan syndrome.

The results provide no evidence that there is an increased incidence of osteoporosis in Marfan syndrome, and further work is needed with other methods of densitometry with measurements at other sites.