Ultrashort echo time spectroscopic imaging (UTESI): an efficient method for quantifying bound and free water.

@article{Diaz2012UltrashortET,
  title={Ultrashort echo time spectroscopic imaging (UTESI): an efficient method for quantifying bound and free water.},
  author={Elizabeth Kay Diaz and Christine B. Chung and Won C Bae and Sheronda M Statum and Richard Znamirowski and Graeme M. Bydder and Jiang Du},
  journal={NMR in biomedicine},
  year={2012},
  volume={25 1},
  pages={
          161-8
        }
}
Biological tissues usually contain distinct water compartments with different transverse relaxation times. In this study, two-dimensional, multi-slice, ultrashort echo time spectroscopic imaging (UTESI) was used with bi-component analysis to detect bound and free water components in musculoskeletal tissues. Feasibility studies were performed using numerical simulation. Imaging was performed on bovine cortical bone, human cadaveric menisci and the Achilles' tendons of volunteers. The simulation… CONTINUE READING
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