Ultrasensitive electrochemical strategy for NT-proBNP detection with gold nanochains and horseradish peroxidase complex amplification.

@article{Zhuo2011UltrasensitiveES,
  title={Ultrasensitive electrochemical strategy for NT-proBNP detection with gold nanochains and horseradish peroxidase complex amplification.},
  author={Ying Zhuo and Wei-jing Yi and Wen-Bing Lian and Ruo Yuan and Yaqin Chai and An Qing Chen and Chuan-min Hu},
  journal={Biosensors & bioelectronics},
  year={2011},
  volume={26 5},
  pages={2188-93}
}
A novel electrochemical immunosensor for sensitive detection of cardiac biomarker N-terminal pro-B-type natriuretic peptide (NT-proBNP) is fabricated based on the nanostructural gold and carbon nanotubes composite as desirable platform for the capture antibodies immobilization and gold nanochains (AuNCs) and horseradish peroxidase (HRP) complex labeled secondary antibodies (AuNCs-HRP-Ab(2)) for signal amplification. The gold nanochains were prepared by the employment of L-ascorbic acid (AA) as… CONTINUE READING

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