Ultrasensitive colorimetric detection of heparin based on self-assembly of gold nanoparticles on graphene oxide.

Abstract

A novel colorimetric method was developed for ultrasensitive detection of heparin based on self-assembly of gold nanoparticles (AuNPs) onto the surface of graphene oxide (GO). Polycationic protamine was used as a medium for inducing the self-assembly of citrate-capped AuNPs on GO through electrostatic interaction, resulting in a shift in the surface plasmon… (More)
DOI: 10.1039/c2an35552c

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