Ultrasensitive and quantitative gold nanoparticle-based immunochromatographic assay for detection of ochratoxin A in agro-products.

@article{Majdinasab2015UltrasensitiveAQ,
  title={Ultrasensitive and quantitative gold nanoparticle-based immunochromatographic assay for detection of ochratoxin A in agro-products.},
  author={Marjan Majdinasab and Mahmoud Sheikh-Zeinoddin and Sabihe Soleimanian-Zad and Peiwu Li and Qi Zhang and Xin Li and Xiaoqian Tang},
  journal={Journal of chromatography. B, Analytical technologies in the biomedical and life sciences},
  year={2015},
  volume={974},
  pages={
          147-54
        }
}
In most cases of mycotoxin detection, quantitation is critical while immunochromatographic strip tests are qualitative in nature. Moreover, the sensitivity of this technique is questioned. In order to overcome these limitations, an ultrasensitive and quantitative immunochromatographic assay (ICA) for rapid and sensitive quantitation of ochratoxin A (OTA) was developed. The assay was based on a competitive format and its sensitivity was improved by using a sensitive and selective OTA monoclonal… CONTINUE READING
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