Ultrapure dialysate reduces plasma levels of beta2-microglobulin and pentosidine in hemodialysis patients.

@article{Furuya2005UltrapureDR,
  title={Ultrapure dialysate reduces plasma levels of beta2-microglobulin and pentosidine in hemodialysis patients.},
  author={Frederic R. Furuya and Hiromichi Kumagai and Masaaki Takahashi and Koji Sano and Akira Hishida},
  journal={Blood purification},
  year={2005},
  volume={23 4},
  pages={
          311-6
        }
}
BACKGROUND beta2-Microglobulin (beta2MG) and carbonyl stress are reported to contribute to the development of dialysis-related amyloidosis. The aim of this study was to determine whether the purity of dialysate affects plasma levels of beta2MG and pentosidine (a surrogate marker of carbonyl stress) in hemodialysis patients. METHODS Sixteen patients on hemodialysis with a polysulfone membrane participated in this study. We switched the dialysate from conventional dialysate (endotoxin level 0… CONTINUE READING

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