Ultralow-intensity near-infrared light induces drug delivery by upconverting nanoparticles.

@article{He2015UltralowintensityNL,
  title={Ultralow-intensity near-infrared light induces drug delivery by upconverting nanoparticles.},
  author={Shuqing He and Kristina Krippes and Sandra Ritz and Zhijun Chen and Andreas Best and Hans-J{\"u}rgen Butt and Volker Mailaender and Si Wu},
  journal={Chemical communications},
  year={2015},
  volume={51 2},
  pages={431-4}
}
Mesoporous silica coated upconverting nanoparticles are loaded with the anticancer drug doxorubicin and grafted with ruthenium complexes as photoactive molecular valves. Drug release was triggered by 974 nm light with 0.35 W cm(-2). Such low light intensity minimized overheating problems and prevented photodamage to biological samples.