Ultrafine particulate matter impairs mitochondrial redox homeostasis and activates phosphatidylinositol 3-kinase mediated DNA damage responses in lymphocytes.

@article{Bhargava2018UltrafinePM,
  title={Ultrafine particulate matter impairs mitochondrial redox homeostasis and activates phosphatidylinositol 3-kinase mediated DNA damage responses in lymphocytes.},
  author={Arpit Bhargava and Shivani Tamrakar and Aniket Aglawe and Harsha Lad and Rupesh K Srivastava and Dinesh Kumar Mishra and Rajnarayan Ramshankar Tiwari and Koel Chaudhury and Irina Yu Goryacheva and Pradyumna Mishra},
  journal={Environmental pollution},
  year={2018},
  volume={234},
  pages={
          406-419
        }
}
Particulate matter (PM), broadly defined as coarse (2.5-10 μm), fine (0.1-2.5 μm) and ultrafine particles (≤0.1 μm), is a major constituent of ambient air pollution. Recent studies have linked PM exposure (coarse and fine particles) with several human diseases including cancer. However, the molecular mechanisms underlying ultrafine PM exposure induced… CONTINUE READING