Ultradonut topology of the nuclear envelope

  • Mehdi Torbatia, Tanmay P. Leleb, Ashutosh Agrawala
  • Published 2016


The nuclear envelope is a unique topological structure formed by lipid membranes in eukaryotic cells. Unlike other membrane structures, the nuclear envelope comprises two concentric membrane shells fused at numerous sites with toroid-shaped pores that impart a “geometric” genus on the order of thousands. Despite the intriguing architecture and vital… (More)

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