Ultra-soft cantilevers and 3-D micro-patterned substrates for contractile bundle tension measurement in living cells.

Abstract

Actin-myosin microfilament bundles or stress-fibers are the principal tension-generating structures in the cell. Their mechanical properties are critical for cell shape, motion, and interaction with other cells and extracellular matrix, but were so far difficult to access in a living cell. Here we propose a micro-fabricated two-component setup for direct… (More)
DOI: 10.1039/c4lc00188e

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