Ultra-slow inactivation of the ionic currents through the membrane of myelinated nerve.

@article{Fox1976UltraslowIO,
  title={Ultra-slow inactivation of the ionic currents through the membrane of myelinated nerve.},
  author={Joe M. Fox},
  journal={Biochimica et biophysica acta},
  year={1976},
  volume={426 2},
  pages={232-44}
}
  • Joe M. Fox
  • Published 1976 in Biochimica et biophysica acta
(1) Voltage-clamp experiments were performed with myelinated fibres isolated from the sciatic nerve of the frog to study slow changes of the specific sodium and potassium currents as a function of membrane (holding) potential and time. (2) The level of the peak sodium current depends on holding potential VH. This dependence can be described by a sigmoidal function uinfinity(VH). The underlying process is called "ultra-slow sodium inactivation" and is different and separable from the short time… CONTINUE READING

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