Ultra-performance liquid chromatography coupled with electrospray ionization/quadrupole time-of-flight mass spectrometry for the rapid analysis of constituents in the traditional Chinese medical formula Danggui San.

@article{Gao2014UltraperformanceLC,
  title={Ultra-performance liquid chromatography coupled with electrospray ionization/quadrupole time-of-flight mass spectrometry for the rapid analysis of constituents in the traditional Chinese medical formula Danggui San.},
  author={Xin Gao and Wenjun Chen Sun and Qiang Fu and Xiaofeng Niu},
  journal={Journal of separation science},
  year={2014},
  volume={37 1-2},
  pages={53-60}
}
In this work, ultra-performance LC with ESI quadrupole TOF-MS (UPLC-ESI-Q-TOF-MS) and automated MetaboLynx analysis was used to rapidly separate and identify the chemical constituents of Danggui San, a traditional Chinese medical formula. The analysis was performed on a Waters UPLC BEH C18 column using a gradient elution system. A hyphenated ESI and Q-TOF analyzer was used for the determination of the accurate mass of the protonated or deprotonated molecule and fragment ions in both positive… CONTINUE READING