Ultra-low fouling and functionalizable zwitterionic coatings grafted onto SiO2 via a biomimetic adhesive group for sensing and detection in complex media.

@article{Brault2010UltralowFA,
  title={Ultra-low fouling and functionalizable zwitterionic coatings grafted onto SiO2 via a biomimetic adhesive group for sensing and detection in complex media.},
  author={Norman D Brault and Changlu Gao and Hong H Xue and Marek Piliarik and Jiř{\'i} Homola and Shaoyi Jiang and Qiuming Yu},
  journal={Biosensors & bioelectronics},
  year={2010},
  volume={25 10},
  pages={2276-82}
}
Non-specific protein binding from human plasma and serum has severely hindered the full capabilities of biosensors concerned with cancer biomarker detection. Currently, there is a strong desire for developing new materials which allow for the convenient attachment of an ultra-low fouling and functionalizable surface coating which can be used for highly sensitive and label-free detection of target analytes directly from complex media. In this work, a short 20 min in situ "graft to" protocol… CONTINUE READING

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