• Corpus ID: 207775719

Ulrike Bingel Analgesic Benefit of the Opioid Remifentanil The Effect of Treatment Expectation on Drug Efficacy : Imaging the

  title={Ulrike Bingel Analgesic Benefit of the Opioid Remifentanil The Effect of Treatment Expectation on Drug Efficacy : Imaging the},
  author={Ulrike Bingel and Vishvarani Wanigasekera and Katja Wiech and R{\'o}is{\'i}n N{\'i} Mhuircheartaigh and Michael C. Lee and Markus Ploner and Irene Tracey},
Evidence from behavioral and self-reported data suggests that the patients' beliefs and expectations can shape both therapeutic and adverse effects of any given drug. [] Key Method The effect of a fixed concentration of the μ-opioid agonist remifentanil on constant heat pain was assessed under three experimental conditions using a within-subject design: with no expectation of analgesia, with expectancy of a positive analgesic effect, and with negative expectancy of analgesia (that is, expectation of…

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