Uliginosin B, a natural phloroglucinol derivative with antidepressant-like activity, increases Na+,K+-ATPase activity in mice cerebral cortex

  • na C. Steina, Liz G. Müllera, +8 authors Stela M.K. Ratesa
  • Published 2016


Uliginosin B, a phloroglucinol isolated from Hypericum polyanthemum Klotzsch ex Reichardt, Hypericaceae, has antidepressant-like effect in the forced swimming test in rodents and inhibits monoamines neuronal reuptake without binding to their neuronal carriers. Studies showed the involvement of Na+,K+ATPase brain activity in depressive disorders, as well as… (More)


4 Figures and Tables