Ulcerative colitis and Crohn's disease in an unselected population of monozygotic and dizygotic twins. A study of heritability and the influence of smoking.

@article{Tysk1988UlcerativeCA,
  title={Ulcerative colitis and Crohn's disease in an unselected population of monozygotic and dizygotic twins. A study of heritability and the influence of smoking.},
  author={Curt Tysk and Eva Pettersson Lindberg and Gunnar J{\"a}rnerot and B Flod{\'e}rus-Myrhed},
  journal={Gut},
  year={1988},
  volume={29 7},
  pages={990-6}
}
By running the Swedish twin registry containing about 25,000 pairs of twins of the same sex together with the central national diagnosis register of hospital inpatients, 80 twin pairs suffering from inflammatory bowel disease were found. In the ulcerative colitis group one of 16 monozygotic pairs was concordant for the disease, but all the other 20 pairs (dizygotic or unknown zygosity) were discordant. In the Crohn's disease group eight of 18 monozygotic pairs and one of 26 dizygotic pairs were… CONTINUE READING

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Preface and acknowledgements

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