Cardiac effects of ephedrine, norephedrine, mescaline, and 3,4-methylenedioxymethamphetamine (MDMA) in mouse and human atrial preparations.
- Biology, MedicineNaunyn-Schmiedeberg's archives of pharmacology
The hallucinogenic drugs ephedrine, norephedrine and MDMA, but not mescaline, increased force of contraction and increased protein phosphorylation presumably, in part, by a release of noradrenaline in isolated human atrial preparations and thus can be regarded as indirect sympathomimetic drugs in the human atrium.
The fourfold discovery of Mescaline (1896–1919)
- ChemistryMonatshefte für Chemie - Chemical Monthly
This is an historical account of the pharmacological, chemical, and anthropological research concerning the molecular makeup of the peyote cactus (Lophophora williamsii) that laid the ground for…
Alkaloids of the Cactaceae — The Classics
- ChemistryNatural Product Communications
Some recorded activities of the 1,2,3,4-tetrahydroisoquinoline alkaloids suggests a need for additional studies, especially in connection with their co-administration with mescaline, as in dried cacti and in beverages prepared from them.
Self-Experiments with Psychoactive Substances: A Historical Perspective.
- PsychologyHandbook of experimental pharmacology
The purpose of this chapter is to highlight the rich tradition of self-experiments (SEs) with psychoactive substances carried out by scientists and therapists for more than a century. Scientifically…
Dark Classics in Chemical Neuroscience: Mescaline.
- BiologyACS chemical neuroscience
Although mescaline binds in a similar concentration range to 5-HT1A and α2A receptors, its low potency is probably responsible for its relative neglect by recreational substance users, as the successful search for structure-activity relationships in the hallucinogen field focused largely on finding more potent analogues.
Unifying Theories of Psychedelic Drug Effects
- PsychologyFront. Pharmacol.
Making an explicit effort to investigate the principles and mechanisms of psychedelic drug effects is a uniquely powerful way to iteratively develop and test unifying theories of brain function.
Aleister Crowley on drugs
While much has been written about the life, work and influence of Aleister Crowley, relatively little attention has been directed to his drug use. This is a little surprising because, not only did he…
Early peyote research an interdisciplinary study
- BiologyEconomic Botany
Present and earlier studies of the Querétaro peyote, Lophophora diffusa, show that this species differs considerably in its alkaloid set-up from L. williamsii, and lends support to the earlier postulation of an independent metabolic pathway to pellotine and anhalidine.
“Ayahuasca,” the South American hallucinogenic drink: An ethnobotanical and chemical investigation
- ChemistryEconomic Botany
Harmine, Harmaline, Tetrahydroharmine and Dimethyltryptamine have been found in the Ayahuasca drink.
The biogeography, ecology, and taxonomy of Lophophora (Cactaceae)
Lophophora, commonly called peyote, has an extensive range within the Chihuahuan Desert of Texas and Mexico and growth characteristics, soils, associated plants, and climate are described.