Ubp2 Regulates Rsp5 Ubiquitination Activity In Vivo and In Vitro

@inproceedings{Lam2013Ubp2RR,
  title={Ubp2 Regulates Rsp5 Ubiquitination Activity In Vivo and In Vitro},
  author={Mandy Hiu Yi Lam and Andrew Emili},
  booktitle={PloS one},
  year={2013}
}
The yeast HECT-family E3 ubiquitin ligase Rsp5 has been implicated in diverse cell functions. Previously, we and others [1], [2] reported the physical and functional interaction of Rsp5 with the deubiquitinating enzyme Ubp2, and the ubiquitin associated (UBA) domain-containing cofactor Rup1. To investigate the mechanism and significance of the Rsp5-Rup1… CONTINUE READING